The continuing saga of complement receptor type 3 (CR3)
نویسندگان
چکیده
منابع مشابه
The Continuing Saga of the AT2 Receptor
Left ventricular hypertrophy (LVH) associated with hypertension puts patients at heightened risk for further cardiovascular complications. There has been lot of interest in the effects of angiotensin II on cardiac tissue because of clinical1,2 and experimental3 evidence of LVH reversal and reduction of cardiovascular risk by inhibition of the reninangiotensin system. Central to this question is...
متن کاملThe continuing saga of MRSA.
In this issue of the Journal, there are 3 papers that expand our understanding of an old enemy, Staphylococcus aureus. They report changes in the prevalence of nasal colonization with S. aureus in the United States, explore the associations among host and bacterial genotypes and nasal carriage or skin infection, and question what defines a community-associated strain of methicillin-resistant S....
متن کاملCutting edge: productive HIV-1 infection of dendritic cells via complement receptor type 3 (CR3, CD11b/CD18).
In the present study, we demonstrate that macrophage-tropic HIV-1 opsonized by complement and limited amounts of anti-HIV-IgG causes up to 10-fold higher productive infection of human monocyte-derived dendritic cells than HIV treated with medium or HIV opsonized by Ab only. Enhanced infection is completely abolished by a mAb specific for the ligand-binding site of CD11b (i.e., alpha-chain of co...
متن کاملPorphyromonas gingivalis interactions with complement receptor 3 (CR3): innate immunity or immune evasion?
Porphyromonas gingivalis is a major oral pathogen associated with periodontal disease. In this paper, we review the mechanism whereby this organism induces a proadhesive signaling pathway for activation of complement receptor 3 (CR3; CD11b/CD18) and discuss its biological significance on the basis of published findings by our lab and other investigators. The proadhesive pathway is initiated whe...
متن کاملArtificial Evolution: A Continuing SAGA
I start with a basic tutorial on Artiicial Evolution, and then show the simplest possible way of implementing this with the Microbial Genetic Algorithm. I then discuss some shortcomings in many of the basic assumptions of the orthodox Genetic Algorithm (GA) community , and give a rather diierent perspective. The basic principles of SAGA (Species Adaptation GAs) will be outlined, and the concept...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1996
ISSN: 0021-9738
DOI: 10.1172/jci118752